Section: Biological and Biochemical Foundations of Living Systems

2) Noncompetitive inhibition differs from uncompetitive inhibition in that a noncompetitive inhibitor binds to an allosteric site on the enzyme and prevents it from catalyzing a reaction, whereas uncompetitive inhibitors bind to the enzyme-substrate complex and prevent catalysis. Increasing the substrate concentration would have which of the following effects?

1. Increasing impact of uncompetitive inhibitor and decreasing concentration of noncompetitive inhibitor
2. Decreasing impact of uncompetitive inhibitor and increasing impact of noncompetitive inhibitor.
3. Increasing impact of uncompetitive inhibitor
4. No effect