Section: Chemical and Physical Foundations of Biological Systems

29) A thin layer chromatography is performed on both the reactants and products of a reaction. It is found that the products have an R_f value that is significantly higher than the reactants. Which of the following could adequately describe this reaction:

1. S_N2 reaction converting an alkyl bromide to an alkyl chloride
2. Addition reaction converting an alkene to an alcohol
3. Nucleophilic acyl substitution reaction converting an ester to an anhydride
4. Elimination reaction converting an alcohol to an alkene